As with any cloud service, access to sufficient bandwidth can be a limitation, especially for the initial migration to the cloud. One way to address this, adopted by suppliers such as Ctera and NetApp, is to provide a local appliance that manages on-going file upload and sync. That is especially useful for branch or remote offices that might lack connectivity.
Ctera emphasizes its support for collaboration, enterprise file-sync-and-share, and its integration with Office. It also uses object storage under the hood, and has multi-cloud support.